Recombinant Rabbit Monoclonal Antibodies: The Key to a New Era of Research

What are Recombinant Rabbit Monoclonal Antibodies?

Recombinant rabbit monoclonal antibodies are antibodies produced through genetic engineering technology, combining the unique advantages of the rabbit immune system with modern biotechnological innovations. They are created by recombining the heavy and light chain genes of rabbit-specific B cells into high-yield mammalian expression vectors, thereby achieving stable and high expression of specific antibodies in vitro.

Technical Features of Recombinant Rabbit Monoclonal Antibodies

• High Affinity and Specificity
  The rabbit immune system has a larger B cell response repertoire and a stronger affinity optimization mechanism, making the affinity of recombinant rabbit monoclonal antibodies for antigen targets 10-100 times higher than that of mouse monoclonal antibodies, with some even reaching the 10^-12 M level.
• Antigen Epitope Recognition Ability
  Rabbit monoclonal antibodies can recognize more antigen epitopes, including subtle differences such as modifications, mutations, and conformational changes, making them particularly suitable for studying post-translational modifications and non-peptide antigens.
• Batch-to-Batch Consistency
  Recombinant rabbit monoclonal antibodies, produced through cloning and expression in vitro, avoid the genetic drift and mutation issues that can occur with traditional hybridoma technology, ensuring batch-to-batch consistency and the reproducibility of experimental results.
• Flexibility and Stability
  Recombinant antibodies are not dependent on the immune characteristics of host animals and can be produced in large quantities through in vitro cell culture to meet various research needs.
• Application Fields

Recombinant rabbit monoclonal antibodies are widely used in experiments such as immunohistochemistry (IHC-P), Western blot (WB), and flow cytometry, providing a powerful tool for cell biology, pathology, and drug development.

Why Choose Recombinant Rabbit Monoclonal Antibodies?

• Higher Sensitivity: Recombinant antibodies optimized through sequence have higher sensitivity and a broader coverage range.
  Innovative Development: A vast antibody library targeting the same antigen can be developed through next-generation sequencing (NGS) technology.
  Dual Value for Clinical and Research: Considered the gold standard for immunohistochemistry in pathology, they also show great potential in diagnostic and therapeutic fields.

Start's proprietary single B cell recombinant rabbit monoclonal antibody technology brings you a premium antibody experience.