α-synuclein His tag Protein, Human

Catalog Number: UA011215 Reactivity: Human Conjugation: Unconjugated Brand: UA BIOSCIENCE

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$100 USD

Size: 25μg 100μg 500μg

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Product Details

Product Specification

Species	Human
Synonyms	alpha-synuclein;Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor (NACP); SNCA; NACP; PARK1;
Accession	P37840
Amino Acid Sequence	Met1-Ala140, with C-10*His
Expression System	E.coli
Molecular Weight	Theoretical: 16.1kDa Actual: 20kDa
Purity	>95% by SDS-PAGE
Endotoxin	<1EU/μg
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4.
Reconstitution	Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage	12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

Background

Alpha-synuclein is a neuronal protein that regulates synaptic vesicle trafficking and subsequent neurotransmitter release. It is abundant in the brain, while smaller amounts are found in the heart, muscle and other tissues. In the brain, alpha-synuclein is found mainly in the axon terminals of presynaptic neurons. Within these terminals, alpha-synuclein interacts with phospholipids and proteins. It plays a role in restricting the mobility of synaptic vesicles, consequently attenuating synaptic vesicle recycling and neurotransmitter release.

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SDS-PAGE

2μg (R: reducing conditions)

ELISA

Immobilized α-synuclein His tag Protein, Human at 2 μg/mL (50 μL/well) can bind α-Synuclein Recombinant Rabbit mAb (S-441-86) (S0B0344) with EC50 of 13.11-21.33 ng/ml.

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α-synuclein His tag Protein, Human