Sirt3 Recombinant Rabbit mAb (S-2005-62)

Sirt3 protein, a member of the sirtuin family, is primarily located in the mitochondria. It is an NAD-dependent deacetylase that plays a crucial role in regulating various cellular processes. Sirt3 can deacetylate numerous target proteins, thereby influencing metabolism, stress resistance and aging. For example, it helps to enhance the activity of certain metabolic enzymes, promoting the breakdown of fatty acids and the generation of energy. Additionally, Sirt3 is involved in the response to oxidative stress, protecting cells from damage caused by reactive oxygen species. Its expression and activity are often altered in various diseases, making it a potential therapeutic target for conditions like metabolic disorders and neurodegenerative diseases.