2 μg(R: reducing conditions)
Product Details
Product Details
Product Specification
Species | Rat |
Synonyms | Immunoglobulin heavy constant epsilon, Ighm |
Accession | A0A0G2JYX2 |
Amino Acid Sequence | Protein sequence (A0A0G2JYX2, Val242-Tyr595, with C-His tag) VPIPAVVEMNPNVSVFIPPRDAFSGPAPRKSRLICEATNFSPKQITVSWLQDGKPVKSGFTTEPVTVEAKGSRPQTYKVISTLTITESDWLNLNVFTCRVDHRGLTFWKNVSSTCAASPSTDILAFPIPPSFADIFLTKSAKLSCLVTNLATYDTLNISWSSKSGEPLETNTKIMESHPNGTFSAVGVASVCMEDWDNRKEFVCTVTHRDLPSPQKKFISKPNEVAKHPPAVYLLPPAREQLILRESATVTCLVKGFSPADIFVQWLQRGQPLSSDKYVTSAPMPEPGAPGLYFTHSILTVTEEEWNSGETYTCVVGHEALPHMVTERTVDKSTGKPTLYNVSLIMSDTGGTCY |
Expression System | HEK293 |
Molecular Weight | Predicted MW: 40.5 kDa Observed MW: 50-60 kDa |
Purity | >95% by SDS-PAGE |
Endotoxin | <0.1EU/μg |
Tag | with C-His tag |
Physical Appearance | Lyophilized Powder |
Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
IGHE has been predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. IGHE has also been predicted to be located in extracellular region, a part of immunoglobulin complex, circulating, and active in external side of plasma membrane. Immunoglobulin E (IgE) are antibodies produced by the immune system. Each type of IgE has specific "radar" for each type of allergen. IgE-mediated food allergies is when the immune system reacts abnormally when exposed to one or more specific foods such as milk, egg, wheat or nuts.
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