Product Details
Product Details
Product Specification
Host | Rabbit |
Antigen | Mouse CXCL1/KC |
Synonyms | Growth-regulated alpha protein; C-X-C motif chemokine 1; Platelet-derived growth factor-inducible protein KC; Secretory protein N51; Gro; Gro1; Mgsa; Scyb1; Cxcl1 |
Immunogen | Recombinant Protein |
Clone Number | SDT-1856-35 |
Antibody Type | Recombinant mAb |
Isotype | IgG |
Application | Sandwich ELISA |
Reactivity | Ms |
Cross Reactivity | No cross reactivity against mouse IL-4, mouse IFN-γ, mouse GM-CSF |
Purification | Protein A |
Concentration | 2 mg/ml |
Conjugation | Unconjugated |
Physical Appearance | Liquid |
Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
Mouse CXCL1, also known as Keratinocyte Chemoattractant (KC), is a chemokine protein that plays a crucial role in immune responses. It is primarily produced by various cell types, including macrophages and endothelial cells, in response to inflammatory stimuli. CXCL1/KC functions by attracting neutrophils to sites of infection or tissue damage, thereby facilitating the immune system's ability to combat pathogens and initiate the healing process. This protein is also involved in the regulation of cell proliferation and angiogenesis, making it an important factor in both acute and chronic inflammatory conditions. Its expression and activity are tightly regulated to ensure appropriate immune responses and tissue homeostasis.
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