Immobilized Human IL-15 Protein, hFc tag at 4 μg/mL (50 μL/well) can bind Biotinylated IL-15R alpha/CD215 Fc&Avi Tag, Human (Cat. No. UA010693) with EC50 of 1.259-1.656 ng/ml.
Human IL-15 Protein, hFc tag
Human IL-15 Protein, hFc tag
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$225 USD
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Interleukin-15, IL15 |
| Accession | P40933 |
| Amino Acid Sequence | Protein sequence (P40933, Asn49-Ser162, with C-hFc tag) NWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS |
| Expression System | HEK293 |
| Molecular Weight | Predicted MW: 38.8 kDa Observed MW: 45-60 kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | with C-hFc tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
Interleukin-15 (IL-15) is a protein that in humans is encoded by the IL15 gene. IL-15 is an inflammatory cytokine with structural similarity to Interleukin-2 (IL-2). Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces the proliferation of natural killer cells, i.e. cells of the innate immune system whose principal role is to kill virally infected cells. IL-15 is constitutively expressed by a large number of cell types and tissues, including monocytes, macrophages, dendritic cells (DC), keratinocytes, fibroblasts, myocyte and nerve cells. As a pleiotropic cytokine, it plays an important role in innate and adaptive immunity.
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Bioactivity
SDS-PAGE
2 μg（R: reducing conditions）
