Immobilized Human IGFBP5 Protein, His Tag at 2 μg/mL (100 μL/well) can bind Human IGF-2 Protein, hFc tag (Cat. No. S0A4045) with EC50 of 3.95-4.63 ng/ml.
Human IGFBP5 Protein, His Tag
Human IGFBP5 Protein, His Tag
Price:
Regular price
$135 USD
Regular price
Sale price
$135 USD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Insulin-like growth factor-binding protein 5, IBP-5, IGF-binding protein 5, IGFBP-5, IBP5 |
| Accession | P24593 |
| Amino Acid Sequence | Protein sequence (P24593, Leu21-Glu272, with C-His Tag) LGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE |
| Expression System | HEK293 |
| Molecular Weight | Predicted MW: 30.3 kDa Observed MW: 40 kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
Insulin-like growth factor-binding protein 5 (IGFBP5) is a key member of the IGFBP family, which regulates the bioavailability and activity of insulin-like growth factors (IGFs). Expressed in various tissues, IGFBP5 modulates cell proliferation, differentiation, and apoptosis through IGF-dependent and IGF-independent mechanisms. It interacts with extracellular matrix components and influences signaling pathways like MAPK and PI3K. IGFBP5 is implicated in physiological processes (e.g., bone development, wound healing) and pathologies, including cancer and fibrosis.
Picture
Picture
Bioactivity
SDS-PAGE
2μg（R: reducing conditions）
