Immobilized Human EPO Protein, hFc Tag at 2 μg/mL (100 μL/well) can bind Recombinant Human Erythropoietin R/EPO-R Protein, C-hFc&His with EC50 of 9-10 ng/ml.
Human EPO Protein, hFc Tag
Human EPO Protein, hFc Tag
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$105 USD
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Erythropoietin |
| Accession | P01588 |
| Amino Acid Sequence | Protein sequence (P01588, Ala28-Arg193, with N-hFc tag) APPRLICDSRVLERYLLEAKEAENITTGCAEHCSLNENITVPDTKVNFYAWKRMEVGQQAVEVWQGLALLSEAVLRGQALLVNSSQPWEPLQLHVDKAVSGLRSLTTLLRALGAQKEAISPPDAASAAPLRTITADTFRKLFRVYSNFLRGKLKLYTGEACRTGDR |
| Expression System | HEK293 |
| Molecular Weight | Predicted MW: 45.3 kDa Observed MW: 60-70 kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | with N-hFc tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
Erythropoietin (EPO) is a glycoprotein hormone primarily produced by the kidneys in response to hypoxia. It stimulates red blood cell production (erythropoiesis) in the bone marrow by binding to the EPO receptor on progenitor cells. Clinically, recombinant human EPO (rhEPO) treats anemia associated with chronic kidney disease and chemotherapy. Beyond hematopoiesis, EPO exhibits tissue-protective effects in the brain and heart.
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Bioactivity
SDS-PAGE
2μg（R: reducing conditions）
