2μg（R: reducing conditions）
Human CCL4 Protein, hFc tag
Human CCL4 Protein, hFc tag
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$220 USD
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | C-C motif chemokine 4, G-26 T-lymphocyte-secreted protein, HC21, Lymphocyte activation gene 1 protein (LAG-1), MIP-1-beta (1-69), Macrophage inflammatory protein 1-beta (MIP-1-beta), PAT 744, Protein H400, SIS-gamma, Small-inducible cytokine A4, T-cell activation protein 2 (ACT-2), LAG1, MIP1B, SCYA4 |
| Accession | P13236 |
| Amino Acid Sequence | Protein sequence (P13236, Ala24-Asn92, with C-hFc tag) APMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQPAVVFQTKRSKQVCADPSESWVQEYVYDLELN |
| Expression System | HEK293 |
| Molecular Weight | Predicted MW: 33.9 kDa Observed MW: 40 kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | with C-hFc tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
CCL4 is a small cytokine that belongs to the CC chemokine subfamily. CCL4 is being secreted under mitogenic signals and antigens and hereby acts as a chemoattractant for natural killer cells, monocytes and various other immune cells in the site of inflamed or damaged tissue. CCL4 is produced by: monocytes, B cells, T cells, NK cells, dendritic cells, neutrophils, fibroblasts, endothelial cells such as vascular smooth muscle cells, brain microvessel endothelial cells, fetal microglia and epithelial cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells.
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