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FGF-9 Protein, Mouse

FGF-9 Protein, Mouse

Catalog Number: UA040097 Brand: UA BIOSCIENCE
Price:
Regular price $164 USD
Regular price Sale price $164 USD
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Product Details

Product Specification


Species Mouse
Antigen FGF-9
Synonyms FGF9,GAF,HBFG-9,MGC119914,MGC119915,SYNS3
Accession P54130
Amino Acid Sequence

Met1-Ser208

Expression System E.coli
Molecular Weight

22-25kDa (Reducing)

Purity

>95% by SDS-PAGE

Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer

20mM Tris, 500mM NaCl, pH8.0

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

· 3 months, -20 to -80℃ under sterile conditions after reconstitution.

· 1 week, 2 to 8℃ under sterile conditions after reconstitution.

· Please avoid repeated freeze-thaw cycles.

Reference

1.Schmahl J. et al. (2004) Fgf9 induces proliferation and nuclearlocalization of FGFR2 in Sertoli precursors during male sex determination.Development. 131(15): 3627-36.

2,Garcès A. et al. (2000) FGF9: a motoneuron survival factor expressed bymedial thoracic and sacral motoneurons. J Neurosci Res. 60(1): 1-9.


Background

FGF9(fibroblastgrowth factor 9, FGF9) is one of the fibroblast growth factor (FGF) familymembers. It is widely distributed in various tissues of human body and involvedin bone development, angiogenesis, embryonic development, damage repair, cellapoptosis, nerve regeneration, tumor growth and other physiological andpathological processes, and can effectively promote mitosis and cell growth.Current evidence suggests that FGF9 may play a prominent role not only in bonedevelopment and growth of cartilage into bone formation and generation, butalso has a significant impact on aspects of ovarian cancer, nerve regeneration,gonadal differentiation, there remains much to be discovered and investigatedon the functions and mechanisms of FGF18.


Picture

Bioactivity

Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The EC50 for this effect is less than 0.5 ng/ml.

SDS-PAGE

5μg (R: reducing condition, N: non-reducing condition).

ELISA

Immobilized FGF-9 Protein, Mouse (Cat. No. UA040097) at 5.0μg/mL (100μL/well) can bind Human FGF R2 (IIIb) protein, Fc Tag with EC50 of 20.82-36.17 ng/mL.