FGF-8e Protein, Human

Catalog Number: UA040049 Reactivity: Human Conjugation: Unconjugated Brand: UA BIOSCIENCE

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$120 USD

Size: 10μg 50μg 100μg 500μg 1mg

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Product Details

Product Specification

Species	Human
Synonyms	FGF-8e, AIGF, HBGF 8e, KAL6
Accession	P55075-1
Amino Acid Sequence	Gln23-Arg233
Expression System	E.coli
Molecular Weight	26kDa
Purity	＞95% by SDS-PAGE and HPLC
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM PB, 150mM NaCl, pH7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1、Valve E M. et al. (2001) Increased expression of FGF-8 isoforms and FGF receptors in human premalignant prostatic intraepithelial neoplasia lesions and prostate cancer. Lab Invest. 81(6): 815-826.

Background

Fibroblast growth factor 8e (FGF-8e), a secreted heparin-binding protein, is a member of the fibroblast growth factor (FGF) family and is an isoform of FGF-8. Alternative splicing of fgf-8 gene gives rise to potentially four (a, b, e, f) different protein isoforms in human. FGF-8 is widely expressed during embryogenesis, and mediates epithelial-mesenchymal transitions. It plays an organizing and inducing role during gastrulation, and regulates patterning of the midbrain/hindbrain, eye, ear, limb and heart in the embryo.