Product Details
Product Details
Product Specification
Species | Mouse |
Synonyms | Small-inducible Cytokine A11 |
Accession | P48298 |
Amino Acid Sequence | His24-Pro97 |
Expression System | E.coli |
Molecular Weight | Approximately 8.4 kDa, a single non-glycosylated polypeptide chain containing 74 amino acids. |
Purity | >97% by SDS-PAGE or HPLC. |
Conjugation | Unconjugated |
Tag | No Tag |
Physical Appearance | Lyophilized powder |
Storage Buffer | 20 mM PB, with 150 mM NaCl, pH 7.4. |
Reconstitution | Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
Stability & Storage | For long term storage, the product should be stored ≤ -20℃. |
Background
Murine CCL11 is belonging to the CC chemokine family. CCL11 was first purified from bronchoalveolar lavage fluid of guinea pigs. It was a strong and specific eosinophil chemoattractant in vitro. It can directly chemotactic for eosinophils, but not for monocytes or neutrophils. Murine CCL11 is approximately 63% identical at the amino acid level to human CCL11. In addition, CCL11 also shows about 60% amino acid sequence identity to human MCPs. CCR3 has been identified to be a specific CCL11 receptor. Recombinant Murine Eotaxin/CCL11 is an 8.4kDa protein containing 74 amino acid residue
