2μg (R: reducing condition, N: non-reducing condition).
BD-5 Protein, Human
BD-5 Protein, Human
Price:
Regular price
$216 USD
Regular price
Sale price
$216 USD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Beta-defensin 105; Beta-defensin 5 (BD-5; DEFB-5); Defensin, beta 105; |
| Accession | Q8NG35 |
| Amino Acid Sequence | Gly28-Ile78 |
| Expression System | E.coli |
| Molecular Weight | 5 kDa (Reducing) |
| Purity | >95% by SDS-PAGE. |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20mM PB, 250mM NaCl, pH6.5 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | Nature. 2003 Apr 3;422(6931):522-6. |
Background
Beta-defensin 5 is a member of the defensin family of antimicrobial peptides that play a crucial role in the innate immune system's defense against pathogens. It is primarily expressed in the gastrointestinal tract, where it contributes to maintaining the mucosal barrier integrity and protecting against microbial invasion. Beta-defensin 5 exhibits potent antimicrobial activity against a wide range of pathogens, including bacteria, fungi, and viruses, by disrupting their cell membranes. In addition to its direct antimicrobial effects, beta-defensin 5 also plays a role in modulating immune responses, promoting wound healing, and maintaining the balance of the gut microbiota.
Picture
Picture
SDS-PAGE
ELISA
Measured by its binding ability in a functional ELISA. When Anti-BD-5 antibody is immobilized 0.5µg/mL (100µL/well), Recombinant Human BD-5 binds with an EC50 of 0.7-1.2ng/ml.
