2 μg（R: reducing conditions）
HIV (HIV1-HXB2) P24 Protein, His tag
HIV (HIV1-HXB2) P24 Protein, His tag
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Product Details
Product Details
Product Specification
| Species | HIV |
| Synonyms | Gag polyprotein, Pr55Gag |
| Accession | P04591 |
| Amino Acid Sequence | Protein sequence (P04591, Pro133-Leu363, with C-His tag) PIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVL |
| Expression System | E.coli |
| Molecular Weight | Predicted MW: 27.4 kDa Observed MW: 25 kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | with C-His tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
The P24 capsid protein is the most abundant HIV protein with each virus containing approximately 1,500 to 3,000 p24 molecules. It is the major structural protein within the capsid, and it is involved in maintaining the structural integrity of the virus and facilitating various stages of the viral life cycle, including viral entry into host cells and the release of new virus particles. Detection of p24 protein's antigen can be used to identify the presence of HIV in a person's blood. After approximately 50 days of infection, the p24 antigen is often cleared from the bloodstream entirely. The HIV-1 p24 capsid protein plays crucial roles throughout the replication cycle, making it an attractive therapeutic target.
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