Human REG1A Protein, His Tag

Lithostathine-1-alpha, also known as Regenerating islet-derived protein 1 alpha (REG1A), is a secreted protein encoded by the REG1A gene. It is primarily produced by the pancreas and plays a role in promoting cell proliferation and regeneration. Its name originates from its initial identification as a protein that inhibits calcium carbonate crystal formation, potentially preventing pancreatic stone formation. However, its primary significance lies in its function as a acute-phase reactant and its strong association with inflammatory and malignant conditions. REG1A is markedly overexpressed in diseases such as chronic pancreatitis and pancreatic ductal adenocarcinoma, making it a promising biomarker for early detection and monitoring of these conditions.