α-Synuclein Recombinant Rabbit mAb (SDT-441-204)
α-Synuclein Recombinant Rabbit mAb (SDT-441-204)
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Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | α-Synuclein |
| Synonyms | Non-A beta component of AD amyloid; α-Syn |
| Immunogen | Recombinant Protein |
| Accession | P37840 |
| Clone Number | SDT-441-204 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Hu, Ms |
| Cross Reactivity | Doesn’t react with GFAP, UCH-L1, gamma-synuclein |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Purity | >95% by HPLC |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
α-Synuclein (α-Syn) is an intrinsically disordered protein whose aggregation in the brain has been significantly implicated in Parkinson’s disease (PD). Beyond the brain, oligomers of α-Synuclein are also found in cerebrospinal fluid (CSF) and blood, where the analysis of these aggregates may provide diagnostic routes and enable a better understanding of disease mechanisms.
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