Immobilized Cynomolgus GDF15, His Tag at 0.2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-GDF15 Antibody, hFc Tag with the EC50 of 6.1 ng/ml determined by ELISA.
GDF15 Protein, Cynomolgus
GDF15 Protein, Cynomolgus
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$750 USD
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Product Details
Product Details
Product Specification
| Species | Cynomolgus |
| Synonyms | GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta; Placental TGF-β; PTGF-β; PTGFBPTGF-β |
| Accession | G7PWZ3 |
| Amino Acid Sequence |
Arg193-Val308 with N-Terminus His tag |
| Expression System | E.coli |
| Molecular Weight |
15-18 kDa
|
| Purity | >95% by Bis-Tris PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 50mM HAc (pH 2.9), 8% trehalose |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 50mM HAc (pH 2.9).
|
| Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. |
Background
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance.
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SDS-PAGE
ELISA
