BDNF Protein, Human/Mouse/Rat
BDNF Protein, Human/Mouse/Rat
Product Details
Product Details
Product Specification
| Species | Human, Mouse, Rat |
| Synonyms | Neurotrophic factor BDNF precursor form,proBDNF, Alternative names,Abrineurin,Brain-derived neurotrophic factor |
| Accession | P23560 |
| Amino Acid Sequence | His129-Arg247 |
| Expression System | E.coli |
| Molecular Weight | 13 KDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.01EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | 20mM PB, 400mM NaCl, pH 7.2. |
| Reconstitution |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Stability & Storage |
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Background
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
