CXCL10/IP-10 Recombinant Rabbit mAb (SDT-1910-136)
CXCL10/IP-10 Recombinant Rabbit mAb (SDT-1910-136)
Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | CXCL10/IP-10 |
| Synonyms | 10 kDa interferon gamma-induced protein (Gamma-IP10; IP-10), Small-inducible cytokine B10 |
| Immunogen | Recombinant Protein |
| Accession | P02778 |
| Clone Number | SDT-1910-136 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Hu |
| Cross Reactivity | No cross-reactivity against GRO alpha, GRO beta, MCP-1 |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
CXCL10, also known as interferon γ-induced protein 10 kDa (IP-10), is a cytokine belonging to the CXC chemokine family. It exerts its biological effects by binding to the CXCR3 receptor and plays a crucial role in immune responses. CXCL10 is a pleiotropic molecule with diverse functions, including promoting the chemotaxis of CXCR3+ cells, inducing apoptosis, regulating cell growth and proliferation, and modulating angiogenesis in infectious diseases, inflammation, and cancer. It is primarily produced by various cell types in response to IFN-γ and is involved in activating T lymphocytes, NK cells, macrophages, dendritic cells, and B cells. Elevated levels of CXCL10 are associated with several pathological conditions, such as autoimmune diseases, viral infections, and tumor development.
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