Flow cytometric analysis of Human CD41a expression on human peripheral blood platelets. Human peripheral blood platelets were stained with either Alexa Fluor® 488 Mouse IgG1, κ Isotype Control (Black line histogram) or SDT Alexa Fluor® 488 Mouse Anti-Human CD41a Antibody (Red line histogram) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
Alexa Fluor® 488 Mouse Anti-Human CD41a Antibody (S-R554)
Alexa Fluor® 488 Mouse Anti-Human CD41a Antibody (S-R554)
Price:
Regular price
$50 USD
Regular price
Sale price
$50 USD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Host | Mouse |
| Antigen | CD41a |
| Synonyms | Integrin alpha-IIb; GPalpha IIb (GPIIb); Platelet membrane glycoprotein IIb; CD41; GP2B; ITGAB; ITGA2B |
| Location | Membrane |
| Accession | P08514 |
| Clone Number | S-R554 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1 |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human peripheral blood platelets |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 488 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD41a, also known as platelet glycoprotein IIb, is a crucial component of the GPIIb/IIIa complex on the platelet membrane. It is a calcium-dependent protein that pairs with CD61 to form the functional fibrinogen receptor, playing a vital role in platelet aggregation and blood clotting. This complex is primarily expressed in normal platelets and megakaryocytes. Additionally, CD41a is one of the first cell surface markers indicative of hematopoietic commitment and is involved in maintaining hematopoietic stem cell activity during embryonic development.
Picture
Picture
FC
