SARS-CoV Spike S2 Protein,His Tag
SARS-CoV Spike S2 Protein,His Tag
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Product Details
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Product Specification
| Synonyms | coronavirus s1 Protein, SARS; coronavirus s2 Protein, SARS; coronavirus spike Protein, SARS; cov spike Protein, SARS; ncov RBD Protein, SARS; ncov s1 Protein, SARS; ncov s2 Protein, SARS; ncov spike Protein, SARS; novel coronavirus RBD Protein, SARS; novel coronavirus s1 Protein, SARS; novel coronavirus s2 Protein, SARS; novel coronavirus spike Protein, SARS; RBD Protein, SARS; S1 Protein, SARS; s2 Protein, SARS; Spike RBD Protein, SARS |
| Accession | QHD43416.1 |
| Expression System | Baculovirus-InsectCells |
| Molecular Weight | 59.65 kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/mg |
| Tag | His Tag |
| Storage Buffer | 20 mM Tris, 300 mM NaCl,10% glycerol, pH 7.5 |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
The SARS-CoV-2 spike glycoprotein is a type I membrane protein, which forms a trimer, anchored to the viral membrane by its transmembrane segment, while decorating the virion surface with it large ectodomain. It binds to the receptor angiotensin-converting enzyme 2 (ACE2) on a host cell and undergo large structural rearrangements to promote membrane fusion. The protein is heavily glycosylated with each protomer containing 22 N-linked glycosylation sites. The full-length S protein of the Wuhan-Hu-1 strain from the initial outbreak has 1273 amino acid residues, including a N-terminus signal peptide, a receptor-binding fragment S1 and a fusion fragment S2.
