SARS-CoV Spike S2 Protein,His Tag
SARS-CoV Spike S2 Protein,His Tag
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$1,800 USD
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Product Details
Product Details
Product Specification
| Synonyms | coronavirus s1 Protein,SARS,coronavirus s2 Protein,SARS,coronavirus spike Protein,SARS,cov spike Protein,SARS,ncov RBD Protein,SARS,ncov s1 Protein,SARS,ncov s2 Protein,SARS,ncov spike Protein,SARS,novel coronavirus RBD Protein,SARS,novel coronavirus s1 Protein,SARS,novel coronavirus s2 Protein,SARS,novel coronavirus spike Protein,SARS,RBD Protein,SARS,S1 Protein,SARS,s2 Protein,SARS,Spike RBD Protein,SARS |
| Accession | QHD43416.1 |
| Expression System | Baculovirus-InsectCells |
| Molecular Weight | 59.65 kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/mg |
| Tag | His Tag |
| Storage Buffer | 20 mM Tris, 300 mM NaCl,10% glycerol, pH 7.5 |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
The SARS-CoV-2 spike glycoprotein is a type I membrane protein, which forms a trimer, anchored to the viral membrane by its transmembrane segment, while decorating the virion surface with it large ectodomain. It binds to the receptor angiotensin-converting enzyme 2 (ACE2) on a host cell and undergo large structural rearrangements to promote membrane fusion. The protein is heavily glycosylated with each protomer containing 22 N-linked glycosylation sites. The full-length S protein of the Wuhan-Hu-1 strain from the initial outbreak has 1273 amino acid residues, including a N-terminus signal peptide, a receptor-binding fragment S1 and a fusion fragment S2.
