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Pacific Blue Mouse Anti-Human CD7 Antibody (S-575-17)

Pacific Blue Mouse Anti-Human CD7 Antibody (S-575-17)

Catalog Number: S0B5126 Application: FCM Reactivity: Human Conjugation: Pacific Blue Brand: Starter
Price:
Regular price $520.00 SGD
Regular price Sale price $520.00 SGD
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Product Details

Product Specification


Host Mouse
Antigen CD7
Synonyms T-cell antigen CD7; GP40; T-cell leukemia antigen; T-cell surface antigen Leu-9; TP41
Immunogen Recombinant Protein
Location Cell membrane
Accession P09564
Clone Number S-575-17
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample human peripheral blood cells
Purification Protein G
Concentration 0.05mg/ml
Conjugation Pacific Blue
Physical Appearance Liquid
Storage Buffer

PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD7, also known as GP40 or T-cell antigen CD7, is a 40 kDa transmembrane glycoprotein that belongs to the immunoglobulin superfamily. It is encoded by the CD7 gene located on chromosome 17 and is expressed on the surface of T cells, natural killer (NK) cells, and their precursors. CD7 plays a crucial role in immune regulation by participating in T-cell activation, providing co-stimulatory signals, and facilitating cell adhesion. It is one of the earliest antigens to appear on T-lymphocyte lineage cells and is highly expressed in various stages of T, B, and myeloid cell differentiation. Additionally, CD7 is involved in T-cell infiltration in tumors, making it an important target for cancer immunotherapy.

Picture

FC

Flow cytometric analysis of Human CD7 expression on human peripheral blood cells. Human peripheral blood cells were stained with Alexa Fluor® 647 Mouse Anti-Human CD3 Antibody and either Pacific Blue Mouse IgG1, κ Isotype Control (Left panel) or SDT Pacific Blue Mouse Anti-Human CD7 Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.

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