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FITC Rat Anti-Mouse CD38 Antibody (S-R549)

FITC Rat Anti-Mouse CD38 Antibody (S-R549)

Catalog Number: S0B5034 Application: FCM Reactivity: Mouse Conjugation: FITC Brand: Starter
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Regular price $143.00 SGD
Regular price Sale price $143.00 SGD
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Product Details

Product Specification


Host Rat
Antigen Mouse CD38
Synonyms 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; cADPR hydrolase 1; I-19; NIM-R5 antigen
Location Membrane
Accession P56528
Clone Number S-R549
Antibody Type Rat mAb
Isotype IgG2a,k
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 0.05mg/ml
Conjugation FITC
Physical Appearance Liquid
Storage Buffer

PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 functions in cell adhesion, signal transduction and calcium signaling. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications including social amnesia possibly related to autism. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism, as well as some genetically determined conditions.

Picture

FC

C57BL/6 mouse splenocytes were stained with Alexa Fluor® 647 Rat Anti-Mouse CD3 Antibody and either FITC Mouse IgG2a, κ Isotype Control (Left panel) or SDT FITC Rat Anti-Mouse CD38 Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.

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