Human DR3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
DR3/TNFRSF25 His&Fc Tag Protein, Human
DR3/TNFRSF25 His&Fc Tag Protein, Human
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$600 USD
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; TNFRSF25; LARD; TR3; TRAMP; WSL-LR |
| Accession | AAI17190 |
| Amino Acid Sequence | Gln25-Gln199 |
| Expression System | HEK293 |
| Molecular Weight |
Predicted MW of 49.80 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
|
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag, His Tag |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, pH 7.4 |
| Stability & Storage |
Valid for 12 months from date of receipt when stored at -80°C. |
Background
Death Receptor 3 (DR3), also known as TNFRSF25, TRAMP, LARD, or WSL-1, is a death-domain-containing TNF-family receptor that, like its closest paralog TNFR1, binds the adaptor molecule TRADD through its cytoplasmic death domain. TRADD recruitment endows DR3 with dual-signaling capability to activate NF−κB and MAP-kinase signaling or alternatively trigger caspase activation and programmed cell death.
Picture
Picture
SDS-PAGE
ELISA
Immobilized Human TNFSF15 Trimer, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human DR3, hFc Tag with the EC50 of 0.67μg/ml determined by ELISA.
