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Anti-CD49d Monoclonal Antibody(Natalizumab)

Anti-CD49d Monoclonal Antibody(Natalizumab)

Catalog Number: S0B060 Application: Functional/Block/Neutralize Brand: Starter
Price:
Regular price $300 USD
Regular price Sale price $300 USD
Size:
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Product Details

Product Specification


Host Human
Accession P13612
Clone Number S-SC023
Antibody Type Recombinant mAb
Isotype IgG4,k
Application Blocking of Integrin alpha-4 signaling Functional assays
Purification Protein A
Concentration 2 mg/ml
Endotoxin <1EU/mg
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer PBS pH7.4, containing no preservative
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Background

Natalizumab, is a monoclonal antibody which targets a protein called α4β1 integrin on white blood cells involved in inflammation. By attaching to integrin, natalizumab is thought to stop white blood cells from entering the brain and spinal cord tissue, thereby reducing inflammation and the resulting nerve damage.

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