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PerCP-Cy5.5 Mouse Anti-Human CD4 Antibody (S-574-16)

PerCP-Cy5.5 Mouse Anti-Human CD4 Antibody (S-574-16)

Catalog Number: S0B1606 Application: FCM Reactivity: Human Conjugation: PerCP-Cy5.5 Brand: Starter
Price:
Regular price $188.00 SGD
Regular price Sale price $188.00 SGD
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Product Details

Product Specification


Host Mouse
Antigen CD4
Synonyms T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3
Immunogen Recombinant Protein
Location Cell membrane
Accession P01730
Clone Number S-574-16
Antibody Type Mouse mAb
Isotype IgG1
Application FCM
Reactivity Hu
Positive Sample human PBMC
Purification Protein G
Concentration 0.2mg/ml
Conjugation PerCP-Cy5.5
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5 μl per million cells in 100μl volume Hu

Background

In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. CD4+ T helper cells are white blood cells that are an essential part of the human immune system. They are often referred to as CD4 cells, T-helper cells or T4 cells. They are called helper cells because one of their main roles is to send signals to other types of immune cells, including CD8 killer cells, which then destroy the infectious particle. If CD4 cells become depleted, for example in untreated HIV infection, or following immune suppression prior to a transplant, the body is left vulnerable to a wide range of infections that it would otherwise have been able to fight.

Picture

FC

Flow cytometric analysis of Human CD4 expression on human PBMC (human peripheral blood mononuclear cell). Human PBMC were stained with Pacific Blue™ Mouse Anti-Human CD8 antibody and either PerCP-Cy5.5 Mouse IgG1 Isotype Control (Left panel) or SDT PerCP-Cy5.5 Mouse Anti-Human CD4 Antibody (Right panel) at 1 μg/test. Fluorescent histograms were gated events with CD3+ T lymphocytes. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.

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