IF shows positive staining in paraffin-embedded human endometrial cancer. Anti-Progesterone Receptor (Alexa Fluor® 555 Conjugate) antibody was used at 1/200 dilution (Red) and incubated overnight at 4°C. Counterstained with DAPI (Blue). Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IF staining protocol.
Progesterone Receptor Recombinant Rabbit mAb (Alexa Fluor® 555 Conjugate) (SDT-R123)
Progesterone Receptor Recombinant Rabbit mAb (Alexa Fluor® 555 Conjugate) (SDT-R123)
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Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | Progesterone Receptor |
| Synonyms | PR, NR3C3 |
| Location | Cytoplasm, Nucleus |
| Accession | P06401 |
| Clone Number | SDT-R123 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IF |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Alexa Fluor® 555 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 0.1% BSA, 0.01% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| IF | 1:200 | null |
Background
Progesterone receptor (PR) is a master regulator in female reproductive tissues that controls developmental processes and proliferation and differentiation during the reproductive cycle and pregnancy. PR also plays a role in progression of endocrine-dependent breast cancer. As a member of the nuclear receptor family of ligand-dependent transcription factors, the main action of PR is to regulate networks of target gene expression in response to binding its cognate steroid hormone, progesterone [PMID: 27380738IF: 4.7 Q1 ].
Picture
Picture
Immunofluorescence
