IFN-γ Recombinant Rabbit mAb (SDT-212-36)
IFN-γ Recombinant Rabbit mAb (SDT-212-36)
Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | IFN-γ |
| Immunogen | Recombinant Protein |
| Accession | P01579 |
| Clone Number | SDT-212-36 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Purity | >95% by HPLC |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| Sandwich ELISA | N/A |
Background
IFN-gamma (Interferon-gamma) is a dimerized soluble cytokine that is the only member of the type II class of interferons. It is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. A primary role for IFN-γ is the activation of macrophages to increase phagocytosis, tumoricidal properties, and intracellular killing of pathogens, particularly bacteria and fungi. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits. The R1 chain is sufficient for binding, but the R2 chain is required for signaling and receptor complex formation.
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