F4/80+ cells were enriched or depleted from C57BL/6 mouse splenocytes. F4/80+ cells were stained with FITC Rat anti- mouse F4/80 (clone:S-R537) and gated on Live+.
Anti-F4/80 Nanobeads, mouse（RUO）
Anti-F4/80 Nanobeads, mouse（RUO）
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Product Specification
| Stability & Storage | Store protected from light at +2 to +8 ℃. Do not freeze. |
Background
F4/80 is a member of epidermal growth factor (EGF) transmembrane 7 (TM7) family and consists of a seven-span transmembrane molecule with a large extracellular, multiple EGF module–containing, domain. F4/80 is considered as one of the most specific cell-surface markers for murine macrophages. Constitutive and high expression of F4/80 is found on most resident tissue macrophages, including spleen, microglia in the brain, Kupffer’s cells in the liver, and Langerhans cells in the skin. In addition, the expression of F4/80 can also be regulated depending on the physiological status of the cell.
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Validation Data
