Immobilized FGF-basic(154aa), Human (Cat. No. UA040007) at 2.5μg/mL (100μL/well) can bind Human FGF-R1/CD331, His Tag (Cat. No. UA020008) with EC50 of 0.049-0.066 μg/ml.
FGF-R1/CD331 His Tag Protein, Human
FGF-R1/CD331 His Tag Protein, Human
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | bFGF-R-1 Protein, BFGFR Protein, CD331 Protein, CEK Protein, FGFBR Protein, FGFR-1 Protein, FLG Protein, FLT-2 Protein, FLT2 Protein, HBGFR Protein, HH2 Protein, HRTFDS Protein, KAL2 Protein, N-SAM Protein, OGD Protein |
| Accession | P11362-7 |
| Amino Acid Sequence | Arg22-Ile376, with C-terminal His |
| Expression System | HEK293 |
| Molecular Weight | 60 -70 kDa(Reducing) |
| Purity | ＞95%, by SDS-PAGE under reducing conditions |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4, 5% trehalose |
| Reconstitution | Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation . |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
FGF-R1, fibroblast growth factor receptor 1, also known as CD331, is a receptor tyrosine kinase whose ligand is a specific member of the fibroblast growth factor family. FGF-R1 is a full-length representative protein, which consists of an extracellular domain, three immunoglobulin-like domains, a hydrophobic transmembrane fragment and a cytoplasmic tyrosine kinase domain. The extracellular domain of FGF-R1 interacts with specific extracellular fibroblast growth factors, initiating a series of downstream signals and affecting cell mitosis and differentiation. FGF-R1 protein is considered to play an important role in the development of nervous system. The protein may also help regulate the growth of long bones, such as large bones in the arms and legs.
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Bioactivity
SDS-PAGE
FGF-R1/CD331 His Tag, Human ,1.5 μg on SDS-PAGE under Non-reducing and reducing condition. The purity is greater than 95%.
RP-HPLC
