Biotinylated SIRP-α His Tag Protein, Human
Biotinylated SIRP-α His Tag Protein, Human
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$560 USD
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Product Details
Product Details
Product Specification
| Species | Human |
| Accession | P78324 |
| Amino Acid Sequence | Glu31-Arg370, with C terminal His&Avitag |
| Expression System | HEK293 |
| Molecular Weight | 55-60 kDa(Reducing) |
| Purity | ＞95%, by SDS-PAGE under reducing conditions |
| Endotoxin | <0.1EU/μg |
| Conjugation | Biotin |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4, 5%trehalose |
| Reconstitution | Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation . |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
Signal regulatory protein α (Signal Regulatory Protein α, SIRP-α), also known as SHPS-1, is a transmembrane protein. SIRPα is highly expressed on the membranes of myeloid cells, such as macrophages, granulocytes, monocytes, and myeloid dendritic cells. It regulates cell migration and phagocytic activities, as well as the formation of immune homeostasis and neural networks.
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Bioactivity
Immobilized CD47 Fc Chimera, Human (Cat. No. UA010006) at 2.5 μg/mL (100 μL/well) can bind Biotinylated SIRP-α His Tag, Human (Cat. No. UA010035) with EC50 of 1.919 μg/mL.
SDS-PAGE
Biotinylated SIRP-α His Tag, Human ,1.5 μg on SDS-PAGE under Non-reducing and reducing condition. The purity is greater than 95%.
