Biotinylated SIRP-α His Tag Protein, Human
Biotinylated SIRP-α His Tag Protein, Human
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$560 USD
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Product Details
Product Details
Product Specification
| Species | Human |
| Accession | P78324 |
| Amino Acid Sequence | Glu31-Arg370, with C terminal His&Avitag |
| Expression System | HEK293 |
| Molecular Weight | 55-60 kDa(Reducing) |
| Purity | ＞95%, by SDS-PAGE under reducing conditions |
| Endotoxin | <0.1EU/μg |
| Conjugation | Biotin |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4, 5%trehalose |
| Reconstitution | Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation . |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
信号调节蛋白α(Signal Regulatory Proteinα, SIRP-α)也称为SHPS-1，是一种跨膜蛋白，SIRPα在髓系细胞膜上高表达，如巨噬细胞、粒细胞、单核细胞和髓样树突状细胞。它调节细胞迁移和吞噬活动，以及免疫稳态和神经网络的形成。
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Bioactivity
Immobilized CD47 Fc Chimera, Human (Cat. No. UA010006) at 2.5 μg/mL (100 μL/well) can bind Biotinylated SIRP-α His Tag, Human (Cat. No. UA010035) with EC50 of 1.919 μg/mL.
SDS-PAGE
Biotinylated SIRP-α His Tag, Human ,1.5 μg on SDS-PAGE under Non-reducing and reducing condition. The purity is greater than 95%.
