1 1

NCAM-1/CD56 (ΔQ609, G610R, M621R) His Tag Protein, Human

NCAM-1/CD56 (ΔQ609, G610R, M621R) His Tag Protein, Human

Catalog Number: UA011224 Brand: UA BIOSCIENCE
Share:
Price:
$335.00 SGD
$335.00 SGD
Size:
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details

Product Details

Product Specification


Species Human
Synonyms Neural cell adhesion molecule 1,CD56,NCAM1,NCAM,Neural Cell Adhesion Molecule,NCAM,CD56 Antigen,N-CAM-1,MSK39,NCAM-1,Antigen Recognized By Monoclonal Antibody 5.1H11
Accession P13591-2
Amino Acid Sequence

Leu20-Gly718 (ΔQ609, Gly610Arg, Met621Arg) with His Tag at C-Terminus
Expression System HEK293
Molecular Weight 90-110kDa (Reducing)
Purity >95% as determined by SDS-PAGE & SEC-HPLC
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized powder
Storage Buffer

PBS, PH7.4, 5% trehalose
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Guven A. et al. (2021) Development and validation of an immunoassay for quantification of NCAM-1 in human plasma. Journal of Pharmaceutical and Biomedical Analysis. 197: 113981.

Background

Neural Cell Adhesion Molecule 1 (NCAM-1), a multifunctional member of the immunoglobulin superfamily, is expressed on neurons, glia, skeletal muscle, and natural killer cells. It plays a key role in cell-cell adhesion and is crucial for nervous system development. Additionally, NCAM-1 is involved in the expansion of T cells and dendritic cells, which are vital for immune surveillance.

Picture

SDS-PAGE

1μg (R: reducing condition, N: non-reducing condition).

SEC-HPLC

The purity of NCAM-1/CD56 (ΔQ609, G610R, M621R) His Tag Protein, Human is greater than 95% as determined by SEC-HPLC.

ELISA

Immobilized NCAM-1/CD56 (ΔQ609, G610R, M621R) His Tag Protein, Human (Cat. No. UA011224) at 1.0μg/mL (100μL/well) can bind Anti-CD56 Reference Antibody (Lorvotuzumab) (Cat. No. UA010990) with EC50 of 1.67-2.42ng/mL.