IL-13 Protein, Human
IL-13 Protein, Human
Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | IL13,ALRH,BHR1,MGC116786,MGC116788,MGC116789,P600,Interleukin-13 |
| Accession | P35225 |
| Amino Acid Sequence | Gly35-Asn146 |
| Expression System | E.coli |
| Molecular Weight | Approximately 12.5 kDa, a single non-glycosylated polypeptide chain containing 112 amino acids. |
| Purity | ＞98% by SDS-PAGE or HPLC. |
| Endotoxin | <0.01EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | 20 mM PB, with 150 mM NaCl, 3% (v/v) Trehalose, pH 7.4. |
| Reconstitution | Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage | For long term storage, the product should be stored ≤ -20℃. |
Background
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Mature human IL-13 shares approximately 58% amino acid sequence identity with mouse and rat IL-13. Despite the low homology, it exhibits cross-species activity between human, mouse, and rat. Recombinant Human IL-13 is a 12.5kDa globular protein containing 112 amino acid.
