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Envelope Glycoprotein B(gB) His Tag Protein, Epstein-Barr virus

Envelope Glycoprotein B(gB) His Tag Protein, Epstein-Barr virus

Catalog Number: UA030096 Brand: UA BIOSCIENCE
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$522.00 SGD
$522.00 SGD
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Product Details

Product Specification


Synonyms Glycoprotein B/gB (EBV)
Accession P03188
Amino Acid Sequence

Gln23-Gly685 with His Tag at the C-Terminus
Expression System HEK293
Molecular Weight 95-100kDa (Reducing)
Purity ＞95% by SDS-PAGE & > 95% SEC-HPLC
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer

PBS, PH7.4, 5% trehalose
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Fang XY, Sun C, Xie C, Cheng BZ, Lu ZZ, Zhao GX, Sui SF, Zeng MS, Liu Z. Structure and Antigenicity of Kaposi's Sarcoma-Associated Herpesvirus Glycoprotein B. Adv Sci (Weinh). 2025 Jul;12(27):e2502231.
2.Wu Q, Chen K, Xue W, Wang G, Yang Y, Li S, Xia N, Chen Y. An insect cell-derived extracellular vesicle-based gB vaccine elicits robust adaptive immune responses against Epstein-Barr virus. Sci China Life Sci. 2025 Mar;68(3):734-745.

Background

Epstein-Barr virus (EBV), or human herpesvirus 4, is a globally prevalent gammaherpesvirus. It is the causative agent of infectious mononucleosis (IM) and is also associated with specific malignancies, including Burkitt's lymphoma (BL) and gastric carcinoma (GC). A key player in EBV infection is glycoprotein B (gB), which facilitates viral entry into epithelial cells by binding to αvβ6/αvβ8 integrins to trigger membrane fusion. This critical function establishes gB as a prominent target for EBV research.

Picture

SDS-PAGE

2μg (R: reducing condition, N:non-reducing condition).

SEC-HPLC

The purity of Envelope Glycoprotein B(gB) His Tag Protein, Epstein-Barr virus is more than 95% determined by SEC-HPLC.