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E2/Envelope2 His Tag Protein, Chikungunya virus CHIKV

E2/Envelope2 His Tag Protein, Chikungunya virus CHIKV

Catalog Number: UA030097 Brand: UA BIOSCIENCE
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Regular price $281.00 SGD
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Product Details

Product Specification


Synonyms E2
Accession A5Y7Y5
Amino Acid Sequence

Ser326-Gln666 with His Tag at the C-Terminus

Expression System HEK293
Molecular Weight 43-55kDa (Reducing)
Purity >95% by SDS-PAGE & > 95% SEC-HPLC
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer

PBS, PH7.4, 5% trehalose

Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

Reference

1.De la Cruz Borthiry FL, Beltrame JS, Cañumil VA, Scheffer F, Bogetti ME, Cella M, Vermeulen M, Gimenez L, Negri Malbrán M, Repetto EM, Cymeryng C, Leguizamon GF, Franchi AM, Ribeiro ML. Chronic mild maternal stress modulates the immune response at the maternal-fetal interface and affects the growth and mortality of the offspring. Placenta. 2025 Oct 3:S0143-4004(25)00711-8.
2.Park KM, Lee YR, Lee NK, Paik HD. Lactiplantibacillus plantarum WB3801 and Lactiplantibacillus plantarum WB3808 Showed Antioxidant Effect and Anti-Apoptosis through Activation of the Keap1/Nrf2/HO-1 Pathway in H2O2-Induced HT-29 Cells. J Microbiol Biotechnol.

Background

Chikungunya virus (CHIKV) envelope protein 2 (E2) plays a central role in viral pathogenesis. This key surface glycoprotein is responsible for receptor binding and facilitating viral entry into host cells. Structurally, E2 forms heterodimers with the E1 fusion protein, which then assemble into the trimeric spike complexes on the viral surface. Given that E2 harbors the virus's principal neutralizing epitopes, it represents a prime candidate antigen for the rational design of vaccines and serological diagnostic assays

Picture

SDS-PAGE

2μg (R: reducing condition, N:non-reducing condition).

SEC-HPLC

The purity of E2/Envelope2 His Tag Protein, Chikungunya virus CHIKV is more than 95% determined by SEC-HPLC.