1μg (R: reducing condition).
Biotinylated B7-H6/NCR3LG1 Fc&Avi Tag Protein, Human
Biotinylated B7-H6/NCR3LG1 Fc&Avi Tag Protein, Human
Price:
Regular price
$516 USD
Regular price
Sale price
$516 USD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | B7-H6,NCR3LG1,B7 Homolog 6 |
| Accession | Q68D85-1 |
| Amino Acid Sequence | Target (Asp25-Ser262) with Human IgG1 Fc &Avi Tag at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 75-90 kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & ＞90% by SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, Human IgG1 Fc |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS PH7.4 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1. Jin Y, Wang X, Kong W, Li X. Association between elevated serum soluble B7-H6 and infection in hemodialysis patients. Clin Exp Nephrol. 2025 May 27. |
Background
B7-H6, a glycosylated member of the B7 family of immune co-stimulatory proteins, is structured with a 238-amino acid extracellular domain containing one Ig-like V domain and one Ig-like C1 domain, a 21-amino acid transmembrane segment, and a 171-amino acid cytoplasmic domain featuring one ITIM, one SH2, and one SH3 motif. Both Ig-like domains undergo N-linked glycosylation. Notably, B7-H6 is expressed in various primary human tumors, such as leukemia, lymphoma, and gastrointestinal stromal tumors, but it is not constitutively expressed in normal tissues.
Picture
Picture
SDS-PAGE
SEC-HPLC
The purity of Biotinylated B7-H6/NCR3LG1 Fc&Avi Tag Protein, Human is greater than 90% as determined by SEC-HPLC.
ELISA
Immobilized NKp30/CD337 Fc Chimera Protein, Human (Cat. No. UA010046) at 10.0μg/mL (100μL/well) can bind Biotinylated B7-H6/NCR3LG1 Fc&Avi Tag Protein, Human (Cat. No. UA011210) with EC50 of 16.43-28.68ng/mL.
