WB result of TBR2/Eomes Recombinant Rabbit mAb
Primary antibody: TBR2/Eomes Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: THP-1 whole cell lysate 20 µg
Lane 2: NK-92 whole cell lysate 20 µg
Negative control: THP-1 whole cell lysate
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 73 kDa
Observed MW: 68, 90 kDa
TBR2/Eomes Recombinant Rabbit mAb (S-1101-123)
TBR2/Eomes Recombinant Rabbit mAb (S-1101-123)
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$100 USD
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Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | TBR2/Eomes |
| Synonyms | Eomesodermin homolog; T-box brain protein 2 (T-brain-2; TBR-2); EOMES |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | O95936 |
| Clone Number | S-1101-123 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | NK-92, mouse embryo, normal mouse E14 fetal brain, normal rat E14 fetal brain |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:10000 | Hu, Ms, Rt |
Background
TBR2/Eomes is a T-box transcription factor that plays crucial roles in various developmental processes. It is preferentially enriched in intermediate progenitors and supports cortical neurogenesis expansion. In the developing cerebral cortex, it is specifically expressed in intermediate progenitors (IPs), which are derived from radial glia progenitors and generate glutamatergic projection neurons. TBR2/Eomes is essential for the differentiation and subtype specification of these neurons, and it regulates the transcriptome by activating or repressing hundreds of direct target genes. Additionally, TBR2/Eomes is involved in the formation and maintenance of certain retinal ganglion cells. It also plays a role in the maintenance of the trophectoderm lineage by sustaining chromatin accessibility and promoting gene regulatory networks.
Picture
Picture
Western Blot
WB result of TBR2/Eomes Recombinant Rabbit mAb
Primary antibody: TBR2/Eomes Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: mouse liver lysate 20 µg
Lane 2: mouse spleen lysate 20 µg
Lane 3: mouse embryo lysate 20 µg
Lane 4: normal mouse E14 fetal brain lysate 20 µg
Negative control: mouse liver lysate; mouse spleen lysate
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 73 kDa
Observed MW: 70, 95 kDa
WB result of TBR2/Eomes Recombinant Rabbit mAb
Primary antibody: TBR2/Eomes Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: rat liver lysate 20 µg
Lane 2: normal rat E14 fetal brain lysate 20 µg
Negative control: rat liver lysate
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 73 kDa
Observed MW: 70, 100 kDa
