Rabbit IgM Recombinant Mouse mAb (S-3624)

Rabbit IgM is a pentameric glycoprotein (approximately 970 kDa, with 10 antigen-binding sites and stabilized by the J chain) that plays a critical role in the humoral immune response of rabbits. As the primary antibody produced during initial immune responses, it functions as a key first responder by binding and neutralizing multivalent antigens, efficiently activating the complement system, promoting phagocytosis, and agglutinating pathogens. Compared to IgG, rabbit IgM exhibits distinct characteristics, including a shorter half-life and limited tissue penetration. Due to its functional properties, it holds significant value in research applications such as antibody production, diagnostic methods including blood typing and infection detection, and emerging therapeutic strategies.