Product Details
Product Details
Product Specification
Host | Mouse |
Synonyms | T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3 |
Immunogen | Recombinant Protein |
Location | Cell membrane |
Accession | P33705 |
Clone Number | S-374-21 |
Antibody Type | Mouse mAb |
Isotype | IgG1,k |
Application | FCM |
Reactivity | CANINE |
Purification | Protein G |
Concentration | 0.002mg/ml |
Conjugation | PE |
Physical Appearance | Liquid |
Storage Buffer | PBS, 0.1% BSA, 0.01% Proclin 300 |
Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
application | dilution | species |
FCM | 5 μl per million cells in 100μl volume |
Background
CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. It is a type of white blood cell that helps fight infection by triggering your immune system to destroy viruses, bacteria, and other germs that may make you sick. CD4 is also a receptor for the HIV virus, and when the virus infects cells with CD4 surface proteins, it depletes the number of T cells, B cells, natural killer cells, and monocytes in the patient's blood.
Picture
Picture
FC
Flow cytometric analysis of Canine CD4 expression on Canine PBMC (Canine peripheral blood mononuclear cell). Canine PBMC were stained with Alexa Fluor® 647 Rat Anti-Canine CD8a antibody and either Phycoerythrin Mouse IgG1, κ Isotype Control (Left panel) or SDT PE Mouse Anti-Canine CD4 Antibody Antibody (Right panel) at 0.01 μg/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
