Product Details
Product Details
Product Specification
| Host | Human |
| Accession | P05231 |
| Clone Number | SDT-R029 |
| Isotype | Human IgG1 |
| Application | CLIA, Sandwich ELISA |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | 20mM PB, 200mM Sucrose, 50mM NaCl, 0.02% Tween80, pH7.5 |
| Stability & Storage | 24 months from manufacturing at ≤-20 °C; 1 month, 2 to 8 °C under sterile conditions. |
Dilution
| application | dilution | species |
| Sandwich ELISA | N/A | null |
Background
Interleukin 6 (IL-6) is a prototypical cytokine for maintaining homeostasis. When homeostasis is disrupted by infections or tissue injuries, IL-6 is produced immediately and contributes to host defense against such emergent stress through activation of acute-phase and immune responses. However, dysregulated excessive and persistent synthesis of IL-6 has a pathological effect on, respectively, acute systemic inflammatory response syndrome and chronic immune-mediated diseases.
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