Product Details
Product Details
Product Specification
Host | Human |
Antigen | IFN-γ |
Accession | P01579 |
Clone Number | SDT-R212 |
Antibody Type | Recombinant mAb |
Application | Sandwich ELISA |
Reactivity | Hu |
Purification | Protein A |
Concentration | 4.011 mg/ml |
Conjugation | Unconjugated |
Physical Appearance | Liquid |
Storage Buffer | PBS pH7.4 |
Stability & Storage | 2 to 8 °C for three month, -20 to -40 °C for six month, -40 to -80 °C for one year. Avoid multiple freeze-thaw cycle. |
Dilution
application | dilution | species |
Sandwich ELISA | N/A | null |
Background
IFN-gamma (Interferon-gamma) is a dimerized soluble cytokine that is the only member of the type II class of interferons. It is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. A primary role for IFN-γ is the activation of macrophages to increase phagocytosis, tumoricidal properties, and intracellular killing of pathogens, particularly bacteria and fungi. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits. The R1 chain is sufficient for binding, but the R2 chain is required for signaling and receptor complex formation.
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