Human IGF-1 Recombinant Mouse mAb (S-3646)
Human IGF-1 Recombinant Mouse mAb (S-3646)
Product Details
Product Details
Product Specification
| Host | Mouse |
| Clone Number | S-3646 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG1 |
| Application | ELISA |
| Reactivity | Hu |
| Purification | Protein G |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| ELISA | 1:5000-1:10000 | Hu |
Background
Insulin-like growth factor 1 (IGF-1), also known as somatomedin C, is a peptide hormone composed of 70 amino acids with a molecular weight of approximately 7.6 kDa. It is primarily produced by the liver and regulated by growth hormone (GH), acting as the main mediator of GH's growth-promoting effects. IGF-1 circulates in the blood, bound to binding proteins that modulate its availability to tissues. It plays a crucial role in promoting cell growth, differentiation, and protein synthesis in various tissues, including muscle, bone, and cartilage. Additionally, IGF-1 has significant effects on brain development and is involved in the regulation of metabolism. Its levels can be used to assess GH status in medical contexts. IGF-1 is a versatile biomarker for diagnosing, monitoring, and managing endocrine (Growth Hormone Disorders), metabolic, oncological, cardiovascular, and neurological conditions. Its clinical application requires careful interpretation in context with patient-specific factors.
