Skip to product information
1 of 1

FITC Mouse Anti-Rat CD44H Antibody (S-R623)

FITC Mouse Anti-Rat CD44H Antibody (S-R623)

Catalog Number: S0B5010 Application: FCM Reactivity: Rat Conjugation: FITC Brand: Starter
Price:
Regular price $143.00 SGD
Regular price Sale price $143.00 SGD
Size:
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details

Product Details

Product Specification


Host Mouse
Antigen Rat CD44H
Synonyms CD44s; CD44A; METAA; RHAMM; CD44; Pgp-1; H-CAM; CD44st; CD44std
Location Cell membrane
Accession P26051
Clone Number S-R623
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Rt
Positive Sample SD Rat splenocytes
Purification Protein A
Concentration 0.2 mg/ml
Conjugation FITC
Physical Appearance Liquid
Storage Buffer

PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Rt

Background

CD44H protein, also known as the standard form of CD44, is a widely expressed cell surface adhesion molecule that plays crucial roles in various cellular processes. It is a transmembrane, highly glycosylated protein primarily involved in cell-cell and cell-matrix interactions, particularly through its binding to hyaluronic acid (HA), a major component of the extracellular matrix. CD44H is expressed on most immune cells, including lymphocytes, monocytes, and granulocytes, and is also found on epithelial, endothelial, and mesenchymal cells. The protein's function includes facilitating cell motility, proliferation, and immune cell activation. In the context of cancer, CD44H is often overexpressed and is considered a marker for cancer stem cells, contributing to tumor development, metastasis, and chemoresistance. Its interaction with HA and other extracellular matrix components is essential for these processes. Additionally, CD44H is involved in the regulation of immune responses, including lymphocyte activation and homing. The protein's cytoplasmic domain interacts with the cytoskeleton and signaling molecules, further modulating cellular behavior.

Picture

FC

Flow cytometric analysis of Rat CD44H expression on SD Rat splenocytes. SD Rat splenocytes were stained with Brilliant Violet 605™ Mouse Anti-Rat CD3 Antibody and either FITC Mouse IgG2a, κ Isotype Control (Left panel) or SDT FITC Mouse Anti-Rat CD44H Antibody (Right panel) at 5μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)