Flow cytometric analysis of Human CD41a expression on human peripheral blood cells. Human peripheral blood cells were stained with SDT APC Mouse Anti-Human CD62P Antibody (S0B5047) at 5 μl/test and either FITC Mouse IgG1 Isotype Control (Left panel) or SDT FITC Mouse Anti-Human CD41a Antibody (Right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
FITC Mouse Anti-Human CD41a Antibody (S-R554)
FITC Mouse Anti-Human CD41a Antibody (S-R554)
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Product Details
Product Details
Product Specification
| Host | Mouse |
| Antigen | CD41a |
| Synonyms | Integrin alpha-IIb; GPalpha IIb (GPIIb); Platelet membrane glycoprotein IIb; CD41; GP2B; ITGAB; ITGA2B |
| Location | Membrane |
| Accession | P08514 |
| Clone Number | S-R554 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1 |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human peripheral blood cells |
| Purification | Protein G |
| Concentration | 0.05mg/ml |
| Conjugation | FITC |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD41a, also known as platelet glycoprotein IIb, is a crucial component of the GPIIb/IIIa complex on the platelet membrane. It is a calcium-dependent protein that pairs with CD61 to form the functional fibrinogen receptor, playing a vital role in platelet aggregation and blood clotting. This complex is primarily expressed in normal platelets and megakaryocytes. Additionally, CD41a is one of the first cell surface markers indicative of hematopoietic commitment and is involved in maintaining hematopoietic stem cell activity during embryonic development.
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