WB result of C1QB Recombinant Rabbit mAb
Primary antibody: C1QB Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: human plasma lysate 5 µg
Secondary antibody: Goat Anti-Rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution Predicted MW: 27 kDa
Observed MW: 27 kDa
C1QB Recombinant Rabbit mAb (S-1248-314)
C1QB Recombinant Rabbit mAb (S-1248-314)
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Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | C1QB |
| Synonyms | Complement C1q subcomponent subunit B |
| Immunogen | Synthetic Peptide |
| Location | Secreted |
| Accession | P02746 |
| Clone Number | S-1248-314 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Positive Sample | human plasma |
| Predicted Reactivity | Bv |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
| IHC-P | 1:200-1:500 | Hu |
Background
C1QB, or Complement C1q Subcomponent B, is a component of the serum complement system C1 complex. It combines with C1QA and C1QC chains, as well as with the precursor enzymes C1r and C1s, to form C1, which is the first component of the serum complement system. The function of C1QB involves its globular head interacting with the Fc region of immune complexes, triggering the complement cascade, leading to the attack and clearance of pathogens. C1QB plays a crucial role in host defense, participating in the recognition and clearance of immune complexes, promotion of phagocytosis, regulation of cytokine production, and influencing T lymphocyte maturation. Additionally, C1QB is involved in tissue repair, tumor immune surveillance, and the homeostasis regulation of the central nervous system. The function of C1QB is essential for maintaining immune balance and preventing autoimmune diseases, and its role in various physiological and pathological processes indicates its complex involvement in immune regulation and cellular processes.
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Picture
Western Blot
Immunohistochemistry
IHC shows positive staining in paraffin-embedded human lung. Anti-C1BQ antibody was used at 1/400 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human placenta. Anti-C1BQ antibody was used at 1/400 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human breast cancer. Anti-C1BQ antibody was used at 1/400 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
