Product Details
Product Details
Product Specification
| Host | Human |
| Antigen | CD20 |
| Synonyms | B-lymphocyte antigen CD20, Bp35, Leukocyte surface antigen Leu-16, MS4A1 |
| Accession | P11836 |
| Clone Number | S-SC005 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG1 |
| Application | Blocking of CD20 signaling Functional assays |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Endotoxin | <2EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Background
Rituximab is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells. It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in non-geriatric patients), rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura, pemphigus vulgaris, myasthenia gravis and Epstein–Barr virus-positive mucocutaneous ulcers.
