Product Details
Product Details
Product Specification
Host | Human |
Antigen | CD20 |
Synonyms | B-lymphocyte antigen CD20, Bp35, Leukocyte surface antigen Leu-16, MS4A1 |
Accession | P11836 |
Clone Number | S-SC005 |
Antibody Type | Recombinant mAb |
Isotype | IgG1 |
Application | Blocking of CD20 signaling Functional assays |
Purification | Protein A |
Concentration | 2 mg/ml |
Endotoxin | <2EU/mg |
Conjugation | Unconjugated |
Physical Appearance | Liquid |
Storage Buffer | PBS pH7.4, containing no preservative |
Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Background
Rituximab is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells. It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in non-geriatric patients), rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura, pemphigus vulgaris, myasthenia gravis and Epstein–Barr virus-positive mucocutaneous ulcers.
