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Human Inhibin beta B Protein, hFc tag

Human Inhibin beta B Protein, hFc tag

Catalog Number: S0A0170 Reactivity: Human Conjugation: Unconjugated Brand: Starter
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Regular price $420 USD
Regular price Sale price $420 USD
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Product Details

Product Specification


Species Human
Synonyms Inhibin beta B chain, Activin beta-B chain, INHBB
Accession P09529
Amino Acid Sequence

Protein sequence (P09529, Ser29-Ala407, with C-hFc tag) SPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA

Expression System HEK293
Molecular Weight Predicted MW: 68.4 kDa Observed MW: 45, 90 kDa
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag with C-hFc tag
Physical Appearance Lyophilized Powder
Storage Buffer

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.

Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

Picture

Bioactivity

Immobilized Recombinant Human Follistatin-like protein 3/FSTL3 Protein at 2 μg/mL (100 μL/well) can bind Human Inhibin beta B Protein, hFc tag with EC50 of 0.29-0.35 μg/ml.

SDS-PAGE

2μg(R: reducing conditions; NR: non-reducing conditions)

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