2μg(R: reducing conditions; NR: non-reducing conditions)
Product Details
Product Details
Product Specification
Species | Human |
Synonyms | Chorionic gonadotropin |
Accession | P01215、P0DN86 |
Amino Acid Sequence | Protein sequence (P01215, Ala25-Ser116) APDVQDCPECTLQENPFFSQPGAPILQCMGCCFSRAYPTPLRSKKTMLVQKNVTSESTCCVAKSYNRVTVMGGFKVENHTACHCSTCYYHKS; Protein sequence (P0DN86, Ser21-Gln165, with C-His tag) SKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRVLQGVLPALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDCGGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGPSDTPILPQ |
Expression System | HEK293 |
Molecular Weight | Predicted MW: 10.2 kDa(CGA)&17.2 kDa(CGB) Observed MW: 20, 33 kDa |
Purity | >95% by SDS-PAGE |
Endotoxin | <1EU/μg |
Conjugation | Unconjugated |
Physical Appearance | Lyophilized powder |
Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose. |
Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
Human chorionic gonadotropin (HCG) is a glycoprotein hormone crucial in mammalian reproduction. Produced by trophoblast cells of the developing placenta after fertilization, it maintains the corpus luteum to sustain progesterone secretion for uterine endometrial maintenance. In research, HCG’s structure, receptor signaling mechanisms, and roles in early pregnancy regulation, trophoblast invasion, and pathological conditions like gestational trophoblastic disease are intensively studied, providing insights into reproductive biology and clinical diagnostics.
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