2μg（R: reducing conditions）
Human FoxO1 Protein, His tag
Human FoxO1 Protein, His tag
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$235 USD
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Forkhead box protein O1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma, FKHR, FOXO1A |
| Accession | Q12778 |
| Amino Acid Sequence | Protein sequence (Q12778, Leu466-Met614, with C-His tag) LTSDSPPHNDIMTPVDPGVAQPNSRVLGQNVMMGPNSVMSTYGSQASHNKMMNPSSHTHPGHAQQTSAVNGRPLPHTVSTMPHTSGMNRLTQVKTPVQVPLPHPMQMSALGGYSSVSSCNGYGRMGLLHQEKLPSDLDGMFIERLDCDM |
| Expression System | E.coli |
| Molecular Weight | Predicted MW: 17.8 kDa Observed MW: 18 kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | with C-His tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
Forkhead box protein O1 (FOXO1), also known as forkhead in rhabdomyosarcoma (FKHR), is a protein that in humans is encoded by the FOXO1 gene. FOXO1 is a transcription factor that plays important roles in regulation of gluconeogenesis and glycogenolysis by insulin signaling, and is also central to the decision for a preadipocyte to commit to adipogenesis. It is primarily regulated through phosphorylation on multiple residues; its transcriptional activity is dependent on its phosphorylation state.
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SDS-PAGE
